A Case of Adolescent Cronkhite-Canada Syndrome

Mikaell Alexandre Gouvea Faria, Bruna Basaglia, Vinicius Quintiliano Moutinho Nogueira, Tatiana Barros Gama Ferraz de Mendonca, Roberto Luiz Kaiser Junior, Idiberto Jose Zotarelli Filho, Luiz Gustavo de Quadros

Abstract


The Cronkhite-Canada syndrome (CCS) was first reported in 1955, since then more than 500 cases have been reported, indicating an estimated incidence of one case per 1 million inhabitants. The syndrome occurs predominantly in male, with a ratio of three males to two females. Because of the rarity of the syndrome, there are no evidence-based therapies and the treatments described include a combination of therapies, but none is consistently effective. Surgery is usually reserved for the treatment of complications. Herein, we present a case of adolescent CCS. The patient was a 15-year-old boy who presented with watery diarrhea with 20 episodes a day, vomiting and abdominal pain for 4 weeks, with a weight loss of 8.0 kg (15.0% of initial weight). Endoscopic examination revealed polyposis in the stomach, duodenum, and colon. CCS was diagnosed and the patient was treated with a combined corticosteroid and metronidazole. Followed up at 8 month after the diagnosis, the patient was asymptomatic.




Gastroenterol Res. 2018;11(1):64-67
doi: https://doi.org/10.14740/gr912w


Keywords


Cronkhite-Canada syndrome; Symptoms; Treatment; Rare case

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