Acute Liver Failure and Myelosuppression due to Parvovirus B19 Infection: A Case Report

Jian Qi Lian, Ye Zhang, Li Liu, Xian Guang Bai, Zhi Jun Liang, Yan Yan Zhao, Ying Min Liang

Abstract


Parvovirus B19 has been associated with different diseases, such as erythema infectiosum, arthropathy and transient aplastic crisis. However, parvovirus B19 infection presenting as hepatic dysfunction and myelosuppression is rarely reported in adult patients. Herein, we report an adult case of acute parvovirus B19 infection presented with acute liver failure and myelosuppression. After being treated with gamma globulin, the patients liver function and bone marrow test improved. We conclude that the parvovirus B19 infection should be considered as a possible cause of acute liver injury and bone marrow suppression. The antibody for B19 virus should be routinely tested in patients with liver dysfunction and/or myelosuppression of unclear etiology.

doi:10.4021/gr2009.03.1278


Keywords


Parvovirus B19; Acute Liver Failure; Myelosuppression

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