Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 11, Number 2, April 2018, pages 95-99

Upper and Lower Gastrointestinal Endoscopic Findings in HIV-Infected Patients in the Era of Highly Active Antiretroviral Therapy

Tables

Table 1. Endoscopy Indications, Gross Findings, and Histological Findings
 
HIV-negative (n = 199)HIV-positive (n = 304)P value
Indications/presenting symptoms
  Abdominal pain/dyspepsia90 (45%)69 (23%)< 0.0001
  Heartburn58 (29%)30 (10%)< 0.0001
  Dysphagia23 (12%)26 (9%)0.2676
  Anemia23 (12%)25 (8%)0.2112
  Variceal screening1 (0.5%)24 (8%)< 0.0001
Endoscopic findings
  Gastric erythema185 (93%)137 (45%)< 0.0001
  Hiatal hernia45 (22%)42 (14%)0.0108
  Peptic ulcer26 (13%)31 (10%)0.3211
  Erosions0 (0%)19 (6%)0.0003
  White plaques0 (0%)12 (4%)0.0046
Histological findings
  Gastritis172 (86%)145 (48%)< 0.0001
  Esophagitis29 (15%)29 (10%)0.0838
  Helicobacter pylori44 (22%)12 (4%)< 0.0001
  Duodenitis24 (12%)18 (6%)0.0150
  Gastric polyp14 (7%)5 (2%)0.0019
  Candida esophagitis0 (0%)8 (3%)0.0179

 

Table 2. Colonoscopy Indications, Gross Findings, and Histological Findings
 
HIV-negative (n = 199)HIV-positive (n = 304)P value
Indications/presenting symptoms
  Screening85 (43%)145 (48%)0.2430
  Gastrointestinal bleeding24 (12%)42 (14%)0.5701
  Anemia22 (11%)17 (6%)0.0253
  Abdominal pain22 (11%)14 (5%)< 0.0001
Colonoscopy findings
  Hemorrhoids96 (48%)148 (49%)0.6307
  Colonic polyps58 (29%)93 (31%)0.9617
  Diverticulosis45 (23%)53 (17%)0.1099
  None/normal4 (2%)17 (6%)0.0499
  Colorectal cancer3 (2%)8 (3%)0.3969
Histological findings
  None/normal96 (48%)118 (39%)0.0366
  Hyperplastic polyp17 (9%)61 (20%)0.0005
  Tubular adenoma27 (14%)30 (10%)0.2008
  Mucosal lymphoid aggregates0 (0%)19 (6%)0.0003
  Colitis9 (5%)10 (3%)0.4792