Gastroenterol Res

Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access

Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc

Journal website http://www.gastrores.org

Original Article

Volume 10, Number 2, April 2017, pages 78-83

Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease

Figure 4. The results of the modified GERD impact scale of patients with different severity of regurgitation.

**Table 1.** Characteristics of the Enrolled Patients With GERD
Severity	Heartburn	Regurgitation
BMI: body mass index; ECJ: esophagocardiac junction; EE: erosive esophagitis; n: numbers; NERD: non-erosive reflux disease. ^aPearson’s Chi-square test. ^bT test.
Mean age (years)	45.81 ± 16.14	46.78 ± 14.72	46.78 ± 11.67	0.851^b	44.98 ± 15.84	48.93 ± 15.08	42.29 ± 14.28	0.094^b
Weight (kg)	65.41 ± 14.11	62.85 ± 11.26	60.11 ± 19.76	0.382^b	66.69 ± 14.51	63.66 ± 12.85	58.29 ± 10.80	0.124^b
BMI (kg/m²)	23.59 ± 4.14	23.06 ± 3.27	22.97 ± 6.12	0.668^b	23.76 ± 4.40	23.42 ± 3.47	22.10 ± 3.80	0.377^b
Gender (male)	52 (47.3%)	30 (55.6%)	3 (33.3%)	0.304^a	42 (51.9%)	35 (51.5%)	8 (33.3%)	0.545^a
Daily habitus
Coffee	63 (57.3%)	38 (70.4%)	4 (44.4%)	0.126^a	43 (53.1%)	48 (70.6%)	14 (58.3%)	0.451^a
Alcohol	50 (45.5%)	19 (35.2%)	3 (33.3%)	0.414^a	40 (49.4%)	22 (32.4%)	10 (41.7%)	0.232^a
Tea	89 (80.9%)	45 (83.3%)	6 (66.7%)	0.530^a	66 (81.5%)	57 (83.3%)	17 (70.8%)	0.438^a
Smoke	15 (13.6%)	11 (20.4%)	1 (11.1%)	0.359^a	13 (16.0%)	9 (13.2%)	5 (20.8%)	0.502^a
Endoscopic findings
NERD	53 (48.2%)	28 (51.9%)	5 (55.6%)	0.611^a	37 (45.7%)	33 (48.5%)	14 (58.3%)	0.522^a
EE	57 (51.8%)	26 (48.1%)	4 (44.4%)		44 (54.3%)	35 (51.5%)	10 (41.7%)
ECJ ulcer	10 (9.1%)	4 (7.4%)	0	0.509^a	4 (4.9%)	10 (14.7%)	0	0.055^a
Hiatal hernia	26 (23.6%)	17 (31.5%)	2 (22.2%)	0.497^a	20 (24.7%)	22 (32.4%)	3 (12.5%)	0.185^a
H. pylori	25 (22.7%)	15 (27.8%)	3 (33.3%)	0.593^a	25 (30.9%)	13 (19.1%)	5 (27.8%)	0.478^a

Table 1. Characteristics of the Enrolled Patients With GERD

Severity

Heartburn

Regurgitation

Mild (n = 110, 63.6%)

Moderate (n = 54, 31.2%)

Advanced (n = 9, 5.2%)

P-value

Mild (n = 81, 46.8%)

Moderate (n = 68, 39.3%)

Advanced (n = 24, 13.9%)

P-value

BMI: body mass index; ECJ: esophagocardiac junction; EE: erosive esophagitis; n: numbers; NERD: non-erosive reflux disease. ^aPearson’s Chi-square test. ^bT test.

Mean age (years)

45.81 ± 16.14

46.78 ± 14.72

46.78 ± 11.67

0.851^b

44.98 ± 15.84

48.93 ± 15.08

42.29 ± 14.28

0.094^b

Weight (kg)

65.41 ± 14.11

62.85 ± 11.26

60.11 ± 19.76

0.382^b

66.69 ± 14.51

63.66 ± 12.85

58.29 ± 10.80

0.124^b

BMI (kg/m²)

23.59 ± 4.14

23.06 ± 3.27

22.97 ± 6.12

0.668^b

23.76 ± 4.40

23.42 ± 3.47

22.10 ± 3.80

0.377^b

Gender (male)

52 (47.3%)

30 (55.6%)

3 (33.3%)

0.304^a

42 (51.9%)

35 (51.5%)

8 (33.3%)

0.545^a

Daily habitus

Coffee

63 (57.3%)

38 (70.4%)

4 (44.4%)

0.126^a

43 (53.1%)

48 (70.6%)

14 (58.3%)

0.451^a

Alcohol

50 (45.5%)

19 (35.2%)

3 (33.3%)

0.414^a

40 (49.4%)

22 (32.4%)

10 (41.7%)

0.232^a

Tea

89 (80.9%)

45 (83.3%)

6 (66.7%)

0.530^a

66 (81.5%)

57 (83.3%)

17 (70.8%)

0.438^a

Smoke

15 (13.6%)

11 (20.4%)

1 (11.1%)

0.359^a

13 (16.0%)

9 (13.2%)

5 (20.8%)

0.502^a

Endoscopic findings

NERD

53 (48.2%)

28 (51.9%)

5 (55.6%)

0.611^a

37 (45.7%)

33 (48.5%)

14 (58.3%)

0.522^a

57 (51.8%)

26 (48.1%)

4 (44.4%)

44 (54.3%)

35 (51.5%)

10 (41.7%)

ECJ ulcer

10 (9.1%)

4 (7.4%)

0.509^a

4 (4.9%)

10 (14.7%)

0.055^a

Hiatal hernia

26 (23.6%)

17 (31.5%)

2 (22.2%)

0.497^a

20 (24.7%)

22 (32.4%)

3 (12.5%)

0.185^a

H. pylori

25 (22.7%)

15 (27.8%)

3 (33.3%)

0.593^a

25 (30.9%)

13 (19.1%)

5 (27.8%)

0.478^a