Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 6, Number 5, October 2013, pages 185-190


Vitamin D and Tumor Necrosis Factor-Alpha Receptor Gene Polymorphisms in Various Hepatitis B Clinical Conditions in Turkey

Tables

Table 1. Subject Demographics and Some Laboratory Test Values
 
VariableAnti-HBs (+)Hepatitis B carrierChronic hepatitis
*P < 0.001.
Gender (F/M)27/3224/3725/38
Age (years; mean ± SD)54.5 ± 15.3*35.8 ± 12.336.6 ± 11.75
ALT (U/L; range, n)-8 - 74 (34)14 - 394* (57)
Viral load (copy/mL; range, n)--70 - 6.27 × 108 (63)

 

Table 2. TNF-α, VDR Apa I and Taq I Polymorphisms in the Investigated Groups
 
Apa I Allele n(%)
AA homozygoteAa heterozygote
Anti-HBs (+)16 (27.1)40 (67.8)
Hepatitis B carrier24 (39.3)28 (45.9)
Chronic hepatitis B22 (34.9)36 (57.1)
Taq I Allele n(%)
TT homozygoteTt heterozygote
Anti-HBs (+)29 (49.2)27 (45.8)
Hepatitis B carrier22 (36.1)31 (50.8)
Chronic hepatitis B29 (46.0)28 (44.4)
TNF G308A Allele n(%)
GG homozygoteGA heterozygote
Anti-HBs (+)52 (88.1)7 (11.9)
Hepatitis B carrier50 (82.0)11 (18.0)
Chronic hepatitis B48 (76.2)14 (22.2)