| Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc |
| Journal website http://www.gastrores.org |
Original Article
Volume 6, Number 1, February 2013, pages 10-16
Stress as a Trigger for Relapses in IBD: A Case-Crossover Study
Tables
| All patients (n = 60) | Relapse during follow-up (n = 25) | No relapse during follow-up (n = 35) | |
|---|---|---|---|
| Male, n/% | 24/40 | 10/36 | 15/43 |
| Female, n/% | 36/60 | 15/64 | 20/57 |
| CD, n/% | 29/48 | 9/36 | 20/57 |
| UC, n/% | 31/52 | 16/64 | 15/43 |
| Age, mean (SD) | 39 (1.31) | 38 (12.53) | 40 (15.91) |
| Localization of disease, n | |||
| Proctitis | 5 | 3 | 2 |
| Proctosigmoiditis | 8 | 5 | 3 |
| Fulminant | 18 | 8 | 10 |
| Colon | 21 | 6 | 15 |
| Colon and small bowel | 2 | 0 | 2 |
| Small bowel | 6 | 3 | 3 |
| Duration of relapse, mean days (SD) | 17 (25.74) | - |
| Analytical approach | No. of subjects | No. of exposed cases during the day prior to onset | Odds ratio | 95% confidence interval |
|---|---|---|---|---|
| Usual frequency | 50 | 19 | 2.48 | 1.07 - 5.78 |
| Matched-pair interval | 50 | 19 | 2.67 | 0.71 - 10.05 |
| Analytical approach | Level of stress | ||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||||
| Odds ratio | 95% confidence interval | Odds ratio | 95% confidence interval | Odds ratio | 95% confidence interval | ||
| Usual frequency (95% CI) | 1.38 | (0.60 - 3.16) | 2.57 | (0.55 - 11.93) | 4.8 | (1.09 - 21.10) | - |
| Matched-pair interval | 1.00 | (0.32 - 3.10) | 3.00 | (0.31 - 28.84) | 4.00 | (0.45 - 35.79) | |