Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 4, Number 2, April 2011, pages 51-57


Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities

Tables

Table 1. Clinical Characteristics of Chronic Renal Failure Patients Receiving Hemodialysis Treatment
 
PatientPrimary renal diseaseDialysis durationUrea*Creatinine*Calcium*Phosphorus*Medication
(months)(mg/dL)a(mg/dL)b(mg/dL)c(mg/dL)d
CGN: chronic glomerulonephritis; PKD: polycystic kidney disease; A: vitamin preparations; normal ranges: (a) 10 - 25 mg/dL, (b) 0.7 - 1.4 mg/dL, (c) 8.5 - 10.5 mg/dL, (d) 3.0 - 4.5 mg/dL. *values obtained the day the patients underwent the manometry examination.
1CGN16812011.98.35.5A
2CGN18013013.68.05.9A
3PKD9619517.18.36.1A
4CGN10815214.29.25.2A
5CGN20417015.38.85.3A
6CGN721029.88.05.1A
7PKD5812011.98.15.4A
8CGN144949.18.55.0A
9CGN2115313.58.34.8A

 

Table 2. Lower Esophageal Sphincter (LES) Pressure and LES Relaxation Duration in Controls and in Patients With Chronic Renal Failure (CRF)
 
LES parametersType of swallowControls (n = 15)CRF patients (n = 9)P-values
The results are shown as median (range).
a: P < 0.05, statistically significant
b: 0.05 < P < 0.1, tendency towards significance
LES resting pressure (mm Hg)21.0 (14.0 - 49.0)42.0 (7.0 - 95.0)0.09b
Dry9.4 (6.6 - 10.8)5.6 (3.4 - 8.3)0.0001a
LES relaxation duration (seconds)Wet9.9 (8.5 - 12.6)7.5 (5.7 - 8.4)< 0.0001a
Syrup9.7 (6.6 - 11.8)7.6 (4.3 - 8.0)0.0001a

 

Table 3. Amplitude, Duration and Velocity of Esophageal Contractions in Controls and in Patients With Chronic Renal Failure (CRF)
 
Contraction parametersType of swallowEsophageal siteControls (n = 15)CRF patients (n = 9)P-values
The results are shown as median (range).
a: P < 0.05, statistically significant
b: 0.05 < P < 0.1, tendency towards significance
Amplitude (mm Hg)Dry1531 (12 - 84)38 (31 - 92)0.008a
1046 (25 - 143)46 (12 - 91)0.59
564 (28 - 187)70 (24 - 111)0.95
Wet1533 (24 - 121)96 (29 - 120)0.01a
1064 (35 - 182)130 (21 - 151)0.19
5116 (50 - 313)150 (23 - 235)0.34
Syrup1536 (20 - 89)56 (24 - 105)0.04a
1072 (30 - 170)68 (20 - 125)0.95
5103 (30 - 224)81 (25 - 210)0.90
Duration (s)Dry153.6 (2.3 - 5.2)3.7 (1.1 - 5.3)0.60
103.9 (3.2 - 5.9)4.5 (2.1 - 6.5)0.19
54.3 (2.8 - 8.8)5.1 (4.2 - 7.3)0.07b
Wet153.5 (2.5 - 5.2)4.2 (1.9 - 5.2)0.09b
104.5 (2.7 - 5.7)5.7 (1.8 - 7.1)0.003a
54.9 (3.4 - 12.7)6.0 (4.5 - 10.1)0.04a
Syrup153.9 (2.2 - 4.9)3.9 (1.1 - 5.3)1.00
104.2 (3.4 - 5.9)5.3 (2.0 - 6.6)0.21
54.7 (3.2 - 10.8)5.3 (4.6 - 7.7)0.09b
Velocity (cm/s)Dry15-103.9 (1.8 - 7.0)3.7 (2.4 - 5.0)0.81
10-54.8 (1.9 - 8.2)2.5 (1.6 - 6.4)0.006a
Wet15-103.2 (1.5 - 5.4)3.3 (1.8 - 4.5)1.00
10-54.0 (1.8 - 6.9)2.5 (1.5 - 10.4)0.09b
Syrup15-103.4 (1.8 - 7.0)2.8 (2.0 - 4.4)0.86
10-54.3 (1.8 - 7.0)2.5 (1.4 - 7.6)0.02a