Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
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Case Report

Volume 2, Number 3, June 2009, pages 178-182

Serrated Adenoma of Gastric Antrum: Alteration of Mucin Expression Profile and its Role in Carcinogenesis

Figures

Figure 1.
Figure 1. Endoscopic view of sessile polyp localized in prepyloric region.
Figure 2.
Figure 2. Serrated glands with a few goblet cells composed of high columnar eosinophilic cells in the serrated component of the adenoma (HE X100).
Figure 3.
Figure 3. MUC2 expression commonly in goblet cells but also slightly in other cells (immunohistochemistry MUC2 X200).
Figure 4.
Figure 4. MUC5AC expression commonly in the distorted glands (immunohistochemistry MUC5AC X200).

Table

Table 1. Histopathologic examination and MUC expression percentages of the follow-up biopsies of the serrated adenoma.
 
Biopsy No.Serrated componentIntestinal metaplasiaGoblet cellsMUC1MUC2MUC5ACMUC6
The immunoreactivity percentages are calculated for all biopsy specimens not for a special histopathological component
13%21.6%80100%37.5%95%66%
223%6.6%60100%50%70%66%
350%13%68100%70%70%100%
463%6.6%4090%75%10%100%