Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
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Original Article

Volume 14, Number 5, October 2021, pages 259-267

The Incidence of Endoscopic Retrograde Cholangiopancreatography-Related Complications in Patients With Liver Transplant: A Meta-Analysis and Systematic Review


Figure 1.
Figure 1. Flow diagram illustrating the selection process.
Figure 2.
Figure 2. Forrest plot, post-ERCP all-complication rate in liver transplant patients. ERCP: endoscopic retrograde cholangiopancreatography; CI: confidence interval.
Figure 3.
Figure 3. Forrest plots, pooled event rate for post-ERCP pancreatitis (a), bleeding (b), infection (c) and cholangitis (d). ERCP: endoscopic retrograde cholangiopancreatography; CI: confidence interval.
Figure 4.
Figure 4. (a) Forrest plot, pooled OR of post-ERCP pancreatitis versus non-transplant patients. (b) Funnel plot of standard error by log OR. OR: odds ratio; ERCP: endoscopic retrograde cholangiopancreatography; CI: confidence interval.


Table 1. Summary of the Studies Used in Meta-Analysis
StudyDesignLocationSettingTime periodNo. of liver transplant patientsNo. of endoscopic retrograde cholangiopancreatographyStudy quality
“*”, “**”, “***” and “****”: Newcastle-Ottawa Scale Star system representing the score given by authors to included studies judged on three broad perspectives: the selection of the study groups; the comparability of the groups; and the ascertainment of either the exposure or outcome of interest for case-control or cohort studies, respectively.
Husing et al [5]Retrospective analysisGermanyPopulation based1998 - 2013157454*******
Ambrus et al [12]Retrospective analysisDenmarkPopulation based2003 - 2012127292********
Law et al [13]Retrospective analysisUSA, SpainPopulation based2000 - 2011, 2003 - 2012301730*********
Sanna et al [14]Retrospective cohort studyItalyPopulation based1990 - 200794150*******
Balderramo et al [15]Retrospective analysisSpainPopulation based2003 - 2010121243*****
Pievsky et al [16]Retrospective analysisUSAPopulation based1997 - 2012120219*******
Singh et al [17]Retrospective reviewUSAPopulation based2005 - 201171159*******
Brown et al [18]Retrospective reviewUSAPopulation based2013 - 20179898*******
Abu Rajab et al [19]Retrospective reviewUSAPopulation based2000 - 2007146146********
Singh [20]Retrospective reviewUSAPopulation based2005 - 2015109235********
Li et al [21]Retrospective reviewChinaPopulation based2015 - 20184848********
Faleschini et al [22]Retrospective analysisItalyPopulation based2000 - 2012142490********
Ramesh et al [23]Retrospective reviewUSAPopulation based2002 - 2013210210********
Catron et al [24]Retrospective ReviewUSAPopulation based2017 - 20184366********