Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 11, Number 3, June 2018, pages 189-194

Low Expression of Transforming Growth Factor β in the Epithelium of Barrett’s Esophagus

Figures

Figure 1.
Figure 1. The value of TGF-β mRNA in the normal esophagus, Barrett’s esophagus (BE), BE with dysplasia, adenocarcinoma (AC), and gastric cardiac epithelium.
Figure 2.
Figure 2. Immunohistochemical analysis of TGF-β in Barrett’s esophagus (BE) (score 0) and gastric cardiac epithelium (score 3) (magnification × 100).
Figure 3.
Figure 3. Immunohistochemical analysis of TGF-β in Barrett’s esophagus (BE), dysplasia, and adenocarcinoma (AC) (all score 0) (magnification × 100).
Figure 4.
Figure 4. The value of TGF-β mRNA of cell lines HETA1, CA-A, CP-C, and OE33.
Figure 5.
Figure 5. The TGF-β Western blotting of cell lines HETA1, CA-A, CP-C, and OE33.

Tables

Table 1. Characteristic of Individuals (BE Patients (n = 30))
 
Basic characteristic
AC: adenocarcinoma; BE: Barrett’s esophagus; BMI: body mass index; LSBE: long-sequment Barrett’s esophagus; SSBE: short-sequment Barrett’s esophagus.
  Age (year)62.00 ± 16.64
  Gender (male)23 (76.7%)
  Body weight (kg)66.78 ± 11.47
  BWI (kg/m2)24.69 ± 3.28
  Waist (cm)90.27 ± 9.40
Endoscopic findings
  SSBE/LSBE26 (86.7%)/4 (13.3%)
  Erosive esophagitis12 (40.0%)
    L.A. grade A/B/C/D6/4/2/0
  Hiatal hernia12 (40.0%)
  H. pylori infection2 (6.7%)
Histological findings
  BE28 (93.4%)
  BE with dysplasia1 (3.3%)
  AC1 (3.3%)

 

Table 2. TGF-β IHC Stain Scores
 
IHC stain01+2+3+Total
GEJ: gastroesophageal junction; IHC: immunohistochemical.
GEJ1084123
Cardiac epithelium1041823