Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 11, Number 2, April 2018, pages 100-105


Clinical Predictors for Repeat Hospitalizations in Left Ventricular Assist Device (LVAD) Patients With Gastrointestinal Bleeding

Figure

Figure 1.
Figure 1. Kaplan-Meier curve showing “survival from re-bleeding”.

Tables

Table 1. Demographics
 
VariablesTotal (102 patients)Patients with GIB (32 patients)Patients without GIB (70 patients)P value
Age53.662.249.5
RaceBlack (%)36 (35.29)7 (21.88)29 (41.43)0.39
White (%)65 (63.73)25 (78.13)40 (57.14)
Other (%)1 (0.98)01 (1.43)
GenderMale (%)83 (81.37)27 (84.38)56 ( 80)0.45
Female (%)19 (18.63)5 (15.63)14 (20)
Average age (range)53.87 (19.2 - 78.9)63.06 (50.0 - 78.9)49.67 (19.2 - 73.7)
Indication for therapyDestination (%)50 (49.02)21 (65.63)29 (41.42)0.04
Bridge to transplant (%)52 (50.98)11 (34.38)41 (58.57)
Type of bleedOvertNA28(87.5)NANA
OccultNA4 (12.5)NANA
Average Hb (g/dL) (range)NA7.88 (4.7 - 13.3)NA
Average INR (range)NA2.1 (1.07 - 4.79)NA
Type of deviceHeartmate II (%)76 (74.5)26 (81.25)50 (71.43)0.4
Heartware (%)25 (24.5)6 (18.75)19 (27.14)
Duraheart (%)1 (0.98)01 (1.43)
MedicationsAspirin (%)94 (92.16)27 (84.38)67 (95.71)1.0
Plavix/prasugrel (%)37 (36.27)13 (40.63)24(34.29)0.71
Coumadin (%)98 (96.08)29 (90.63)69 (98.57)0.02

 

Table 2. Results Showing Odds Ratio (OR) for Readmission for GIB in LVAD Patients
 
ParameterLevelEstimated ORLower limit 95% CIUpper limit 95% CIP value
LOS: length of hospital stay; INR: international normalized ratio; *Showing statistically significant variables.
SexMale10.369*1.81559.2410.0085*
Intention to treatBridge to transplant0.073*0.190.2730.0001*
Overt vs. occultOccult2.1850.6777.056Not significant
Early endoscopy (< 48 h)Yes0.430*0.1860.9920.048*
EtiologyIschemic0.5710.2601.254Not significant
LOSEach additional day0.831*0.7120.9790.092
INR level on admissionEach 1 point over normal3.580*1.4638.7590.052