Relatively Long Survival in Hepatocellular Carcinoma Presenting With Carcinoid Syndrome

Sylvester Chuks Nwokediuko, Ijoma Uchenna, Ofoegbu Esther, Okafor Okechukwu, Onuh Augustine, Ajuyah Charity

Abstract


Hepatocelluar carcinoma is one of the commonest cancers in Nigeria. Some patients may manifest a variety of paraneoplastic syndromes. Carcinoid syndrome is an extremely rare presentation of hepatocellular carcinoma. A 57-year old man presented with recurrent facial flushing and diarrhea, tricuspid regurgitation, and very high level of urinary hydroxyindoleacetic acid (HIAA) as the first manifestation of a multicentric hepatic lesion which proved histologically to be hepatocellular carcinoma. The lesions also exhibited arterial hypervascularization on contrast enhanced computerized tomography. The patient is still alive after 6 years of symptoms.




doi:10.4021/gr2010.02.171w


Keywords


Carcinoid syndrome; Hepatocelluar carcinoma; Paraneoplastic syndrome; Survival

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Gastroenterology Research, bimonthly, ISSN 1918-2805 (print), 1918-2813 (online), published by Elmer Press Inc.     
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